Biography- Terrence Early MD
After completing medical school at Duke University and a psychiatric residency at Washington University, I joined the
faculty at Washington University and initially did research in brain imaging and cognitive studies. In 1993, I moved to
the University of Texas Medical Branch in Galveston, where I became interested in developing novel treatments for
refractory psychiatric illness. Beginning in 1999 I received grants from Narsad and the Stanley Foundation to
compare high dose sevoflurane to electroconvulsive therapy for treatment resistant mood disorders. This was a
replication of a finding reported by Dr. Gerhard Langer using isoflurane, which has recently been replicated by Dr.
Howard Weeks and his collaborators at the University of Utah using isoflurane and propofol. Like these investigators,
I found it impossible to disseminate this useful treatment, which is as effective as ECT but does not cause any
cognitive side effects.